Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

The interleukin (IL)-13 pathway and its associated transcription factor, signal transducer and activator of transcription 6 (STAT6), have been clearly implicated in the pathogenesis of bronchial asthma. We have developed a system to effectively screen the STAT6 gene for targeting with small interfer...

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Detalles Bibliográficos
Autores principales: Healey, Gareth D, Zinnen, Shawn, Lockridge, Jennifer A, Richards, Ivan, Evans, Neil, Walker, William
Formato: Texto
Lenguaje:English
Publicado: Library Publishing Media 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943664/
https://www.ncbi.nlm.nih.gov/pubmed/20927184

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