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Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes
Triglycerides have a limited solubility, around 3%, in phosphatidylcholine lipid bilayers. Using millisecond-scale course grained molecular dynamics simulations, we show that the model lipid bilayer can accommodate a higher concentration of triolein (TO) than earlier anticipated, by sequestering tri...
Autores principales: | Khandelia, Himanshu, Duelund, Lars, Pakkanen, Kirsi I., Ipsen, John H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943900/ https://www.ncbi.nlm.nih.gov/pubmed/20877640 http://dx.doi.org/10.1371/journal.pone.0012811 |
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