Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

The chromatin remodelling factor chromodomain helicase DNA-binding protein 4 (CHD4) is a catalytic subunit of the NuRD transcriptional repressor complex. Here, we reveal novel functions for CHD4 in the DNA-damage response (DDR) and cell-cycle control. We show that CHD4 mediates rapid poly(ADP-ribose...

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Detalles Bibliográficos
Autores principales: Polo, Sophie E, Kaidi, Abderrahmane, Baskcomb, Linda, Galanty, Yaron, Jackson, Stephen P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944064/
https://www.ncbi.nlm.nih.gov/pubmed/20693977
http://dx.doi.org/10.1038/emboj.2010.188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944064/
https://www.ncbi.nlm.nih.gov/pubmed/20693977
http://dx.doi.org/10.1038/emboj.2010.188

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