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Side effects of chaperone gene co-expression in recombinant protein production
Insufficient availability of molecular chaperones is observed as a major bottleneck for proper protein folding in recombinant protein production. Therefore, co-production of selected sets of cell chaperones along with foreign polypeptides is a common approach to increase the yield of properly folded...
Autores principales: | Martínez-Alonso, Mónica, García-Fruitós, Elena, Ferrer-Miralles, Neus, Rinas, Ursula, Villaverde, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944165/ https://www.ncbi.nlm.nih.gov/pubmed/20813055 http://dx.doi.org/10.1186/1475-2859-9-64 |
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