Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

BACKGROUND: Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. An animal model of chondrosarcoma has been established - namely, the Swarm Rat Chondrosarcoma (SR...

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Detalles Bibliográficos
Autores principales: Hamm, Christopher A, Stevens, Jeff W, Xie, Hehuang, Vanin, Elio F, Morcuende, Jose A, Abdulkawy, Hakeem, Seftor, Elisabeth A, Sredni, Simone T, Bischof, Jared M, Wang, Deli, Malchenko, Sergey, de Fatima Bonaldo, Maria, Casavant, Thomas L, Hendrix, Mary JC, Soares, Marcelo B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944175/
https://www.ncbi.nlm.nih.gov/pubmed/20809981
http://dx.doi.org/10.1186/1471-2407-10-471

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