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Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations
In this paper, we illustrate how advanced computational modelling and simulation can be used to investigate drug-induced effects on cardiac electrophysiology and on specific biomarkers of pro-arrhythmic risk. To do so, we first perform a thorough literature review of proposed arrhythmic risk biomark...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society Publishing
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944395/ https://www.ncbi.nlm.nih.gov/pubmed/20478918 http://dx.doi.org/10.1098/rsta.2010.0083 |