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Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of most genes and often lack DNA methylation. Querying their apparent importance, the number of CGIs is reported to vary widely in different species and many do not co-localise with annotated promoters. We set out to qu...
Autores principales: | Illingworth, Robert S., Gruenewald-Schneider, Ulrike, Webb, Shaun, Kerr, Alastair R. W., James, Keith D., Turner, Daniel J., Smith, Colin, Harrison, David J., Andrews, Robert, Bird, Adrian P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944787/ https://www.ncbi.nlm.nih.gov/pubmed/20885785 http://dx.doi.org/10.1371/journal.pgen.1001134 |
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