HLA Class I Binding of HBZ Determines Outcome in HTLV-1 Infection

CD8(+) T cells can exert both protective and harmful effects on the virus-infected host. However, there is no systematic method to identify the attributes of a protective CD8(+) T cell response. Here, we combine theory and experiment to identify and quantify the contribution of all HLA class I allel...

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Detalles Bibliográficos
Autores principales: MacNamara, Aidan, Rowan, Aileen, Hilburn, Silva, Kadolsky, Ulrich, Fujiwara, Hiroshi, Suemori, Koichiro, Yasukawa, Masaki, Taylor, Graham, Bangham, Charles R. M., Asquith, Becca
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944806/
https://www.ncbi.nlm.nih.gov/pubmed/20886101
http://dx.doi.org/10.1371/journal.ppat.1001117

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