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Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence

Toll-like receptor signaling requires functional Toll/interleukin-1 (IL-1) receptor (TIR) domains to activate innate immunity. By producing TIR homologous proteins, microbes inhibit host response induction and improve their own survival. The TIR homologous protein TcpC was recently identified as a v...

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Detalles Bibliográficos
Autores principales:	Yadav, Manisha, Zhang, Jingyao, Fischer, Hans, Huang, Wen, Lutay, Nataliya, Cirl, Christine, Lum, Josephine, Miethke, Thomas, Svanborg, Catharina
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944809/ https://www.ncbi.nlm.nih.gov/pubmed/20886104 http://dx.doi.org/10.1371/journal.ppat.1001120

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