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Opto-Current-Clamp Actuation of Cortical Neurons Using a Strategically Designed Channelrhodopsin
BACKGROUND: Optogenetic manipulation of a neuronal network enables one to reveal how high-order functions emerge in the central nervous system. One of the Chlamydomonas rhodopsins, channelrhodopsin-1 (ChR1), has several advantages over channelrhodopsin-2 (ChR2) in terms of the photocurrent kinetics....
Autores principales: | Wen, Lei, Wang, Hongxia, Tanimoto, Saki, Egawa, Ryo, Matsuzaka, Yoshiya, Mushiake, Hajime, Ishizuka, Toru, Yawo, Hiromu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944835/ https://www.ncbi.nlm.nih.gov/pubmed/20886118 http://dx.doi.org/10.1371/journal.pone.0012893 |
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