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Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

BACKGROUND: The mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the microenvironment and how this response varies...

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Detalles Bibliográficos
Autores principales: Tilghman, Robert W., Cowan, Catharine R., Mih, Justin D., Koryakina, Yulia, Gioeli, Daniel, Slack-Davis, Jill K., Blackman, Brett R., Tschumperlin, Daniel J., Parsons, J. Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944843/
https://www.ncbi.nlm.nih.gov/pubmed/20886123
http://dx.doi.org/10.1371/journal.pone.0012905