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Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype
BACKGROUND: The mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the microenvironment and how this response varies...
Autores principales: | Tilghman, Robert W., Cowan, Catharine R., Mih, Justin D., Koryakina, Yulia, Gioeli, Daniel, Slack-Davis, Jill K., Blackman, Brett R., Tschumperlin, Daniel J., Parsons, J. Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944843/ https://www.ncbi.nlm.nih.gov/pubmed/20886123 http://dx.doi.org/10.1371/journal.pone.0012905 |
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