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β2-Syntrophin Is a Cdk5 Substrate That Restrains the Motility of Insulin Secretory Granules
The molecular basis for the interaction of insulin granules with the cortical cytoskeleton of pancreatic β-cells remains unknown. We have proposed that binding of the granule protein ICA512 to the PDZ domain of β2-syntrophin anchors granules to actin filaments and that the phosphorylation/dephosphor...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944849/ https://www.ncbi.nlm.nih.gov/pubmed/20886068 http://dx.doi.org/10.1371/journal.pone.0012929 |