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Neurenteric cysts of the spine

Neurenteric cysts account for 0.7-1.3% of spinal axis tumors. These rare lesions result from the inappropriate partitioning of the embryonic notochordal plate and presumptive endoderm during the third week of human development. Heterotopic rests of epithelium reminiscent of gastrointestinal and resp...

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Autores principales: Savage, Jesse J., Casey, James N., McNeill, Ian T., Sherman, Jonathan H.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944853/
https://www.ncbi.nlm.nih.gov/pubmed/20890417
http://dx.doi.org/10.4103/0974-8237.65484
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author Savage, Jesse J.
Casey, James N.
McNeill, Ian T.
Sherman, Jonathan H.
author_facet Savage, Jesse J.
Casey, James N.
McNeill, Ian T.
Sherman, Jonathan H.
author_sort Savage, Jesse J.
collection PubMed
description Neurenteric cysts account for 0.7-1.3% of spinal axis tumors. These rare lesions result from the inappropriate partitioning of the embryonic notochordal plate and presumptive endoderm during the third week of human development. Heterotopic rests of epithelium reminiscent of gastrointestinal and respiratory tissue lead to eventual formation of compressive cystic lesions of the pediatric and adult spine. Histopathological analysis of neurenteric tissue reveals a highly characteristic structure of columnar or cuboidal epithelium with or without cilia and mucus globules. Patients with symptomatic neurenteric cysts typically present in the second and third decades of life with size-dependent myelopathic and/or radicular signs. Magnetic resonance imaging and computed tomography are essential diagnostic tools for the delineation of cyst form and overlying osseous architecture. A variety of approaches have been employed in the treatment of neurenteric cysts each with a goal of total surgical resection. Although long-term outcome analyses are limited, data available indicate that surgical intervention in the case of neurenteric cysts results in a high frequency of resolution of neurological deficit with minimal morbidity. However, recurrence rates as high as 37% have been reported with incomplete resection secondary to factors such as cyst adhesion to surrounding structure and unclear dissection planes. Here we present a systematic review of English language literature from January 1966 to December 2009 utilizing MEDLINE with the following search terminology: neurenteric cyst, enterogenous cyst, spinal cord tumor, spinal dysraphism, intraspinal cyst, intramedullary cyst, and intradural cyst. In addition, the references of publications returned from the MEDLINE search criteria were surveyed in order to examine other pertinent reports.
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spelling pubmed-29448532010-09-24 Neurenteric cysts of the spine Savage, Jesse J. Casey, James N. McNeill, Ian T. Sherman, Jonathan H. J Craniovertebr Junction Spine Review Article Neurenteric cysts account for 0.7-1.3% of spinal axis tumors. These rare lesions result from the inappropriate partitioning of the embryonic notochordal plate and presumptive endoderm during the third week of human development. Heterotopic rests of epithelium reminiscent of gastrointestinal and respiratory tissue lead to eventual formation of compressive cystic lesions of the pediatric and adult spine. Histopathological analysis of neurenteric tissue reveals a highly characteristic structure of columnar or cuboidal epithelium with or without cilia and mucus globules. Patients with symptomatic neurenteric cysts typically present in the second and third decades of life with size-dependent myelopathic and/or radicular signs. Magnetic resonance imaging and computed tomography are essential diagnostic tools for the delineation of cyst form and overlying osseous architecture. A variety of approaches have been employed in the treatment of neurenteric cysts each with a goal of total surgical resection. Although long-term outcome analyses are limited, data available indicate that surgical intervention in the case of neurenteric cysts results in a high frequency of resolution of neurological deficit with minimal morbidity. However, recurrence rates as high as 37% have been reported with incomplete resection secondary to factors such as cyst adhesion to surrounding structure and unclear dissection planes. Here we present a systematic review of English language literature from January 1966 to December 2009 utilizing MEDLINE with the following search terminology: neurenteric cyst, enterogenous cyst, spinal cord tumor, spinal dysraphism, intraspinal cyst, intramedullary cyst, and intradural cyst. In addition, the references of publications returned from the MEDLINE search criteria were surveyed in order to examine other pertinent reports. Medknow Publications 2010 /pmc/articles/PMC2944853/ /pubmed/20890417 http://dx.doi.org/10.4103/0974-8237.65484 Text en © Journal of Craniovertebral Junction and Spine http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Savage, Jesse J.
Casey, James N.
McNeill, Ian T.
Sherman, Jonathan H.
Neurenteric cysts of the spine
title Neurenteric cysts of the spine
title_full Neurenteric cysts of the spine
title_fullStr Neurenteric cysts of the spine
title_full_unstemmed Neurenteric cysts of the spine
title_short Neurenteric cysts of the spine
title_sort neurenteric cysts of the spine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944853/
https://www.ncbi.nlm.nih.gov/pubmed/20890417
http://dx.doi.org/10.4103/0974-8237.65484
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