Programmed Death-1 Expression on Epstein Barr Virus Specific CD8+ T Cells Varies by Stage of Infection, Epitope Specificity, and T-Cell Receptor Usage

BACKGROUND: Programmed Death-1 (PD-1) is an inhibitory member of the CD28 family of molecules expressed on CD8+ T cells in response to antigenic stimulation. To better understand the role of PD-1 in antiviral immunity we examined the expression of PD-1 on Epstein-Barr virus (EBV) epitope-specific CD...

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Detalles Bibliográficos
Autores principales: Greenough, Thomas C., Campellone, Shalyn C., Brody, Robin, Jain, Surbhi, Sanchez-Merino, Victor, Somasundaran, Mohan, Luzuriaga, Katherine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944873/
https://www.ncbi.nlm.nih.gov/pubmed/20886079
http://dx.doi.org/10.1371/journal.pone.0012926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944873/
https://www.ncbi.nlm.nih.gov/pubmed/20886079
http://dx.doi.org/10.1371/journal.pone.0012926

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