A Multi-Parameter, High-Content, High-Throughput Screening Platform to Identify Natural Compounds that Modulate Insulin and Pdx1 Expression

Diabetes is a devastating disease that is ultimately caused by the malfunction or loss of insulin-producing pancreatic beta-cells. Drugs capable of inducing the development of new beta-cells or improving the function or survival of existing beta-cells could conceivably cure this disease. We report a...

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Detalles Bibliográficos
Autores principales: Hill, Jessica A., Szabat, Marta, Hoesli, Corinne A., Gage, Blair K., Yang, Yu Hsuan C., Williams, David E., Riedel, Michael J., Luciani, Dan S., Kalynyak, Tatyana B., Tsai, Kevin, Ao, Ziliang, Andersen, Raymond J., Warnock, Garth L., Piret, James M., Kieffer, Timothy J., Johnson, James D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944895/
https://www.ncbi.nlm.nih.gov/pubmed/20886041
http://dx.doi.org/10.1371/journal.pone.0012958

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