Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis

INTRODUCTION: Osteoporosis (OP) increases cartilage damage in a combined rabbit model of OP and osteoarthritis (OA). Accordingly, we assessed whether microstructure impairment at subchondral bone aggravates cartilage damage in this experimental model. METHODS: OP was induced in 20 female rabbits, by...

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Detalles Bibliográficos
Autores principales: Bellido, Miriam, Lugo, Laura, Roman-Blas, Jorge A, Castañeda, Santos, Caeiro, Jose R, Dapia, Sonia, Calvo, Emilio, Largo, Raquel, Herrero-Beaumont, Gabriel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945051/
https://www.ncbi.nlm.nih.gov/pubmed/20678201
http://dx.doi.org/10.1186/ar3103

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