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Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor β-chain

INTRODUCTION: The Vβ12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)-specific T-cell receptor (TCR) β-chain and cons...

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Detalles Bibliográficos
Autores principales:	Merky, Patrick, Batsalova, Tsvetelina, Bockermann, Robert, Dzhambazov, Balik, Sehnert, Bettina, Burkhardt, Harald, Bäcklund, Johan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945055/ https://www.ncbi.nlm.nih.gov/pubmed/20682070 http://dx.doi.org/10.1186/ar3108

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