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A new tool for detection of type I interferon activation in systemic lupus erythematosus

The IFN-I pathway is activated in systemic lupus erythematosus (SLE) and appears to be important in the pathogenesis of the disease. As a result, several clinical trials of anti-IFN monoclonal antibodies, which hold promise to control the disease, have been launched. Additionally, activation of IFN-...

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Detalles Bibliográficos
Autores principales: Kirou, Kyriakos A, Kalliolias, George D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945060/
https://www.ncbi.nlm.nih.gov/pubmed/20815919
http://dx.doi.org/10.1186/ar3114