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A new tool for detection of type I interferon activation in systemic lupus erythematosus
The IFN-I pathway is activated in systemic lupus erythematosus (SLE) and appears to be important in the pathogenesis of the disease. As a result, several clinical trials of anti-IFN monoclonal antibodies, which hold promise to control the disease, have been launched. Additionally, activation of IFN-...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945060/ https://www.ncbi.nlm.nih.gov/pubmed/20815919 http://dx.doi.org/10.1186/ar3114 |