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Polymorphisms in the glucocorticoid receptor gene that modulate glucocorticoid sensitivity are associated with rheumatoid arthritis
INTRODUCTION: The glucocorticoid receptor (GR) plays an important regulatory role in the immune system. Four polymorphisms in the GR gene are associated with differences in glucocorticoid (GC) sensitivity; the minor alleles of the polymorphisms N363 S and BclI are associated with relative hypersensi...
Autores principales: | van Oosten, Manon JM, Dolhain, Radboud JEM, Koper, Jan W, van Rossum, Elisabeth FC, Emonts, Marieke, Han, Khik H, Wouters, Jacques MGW, Hazes, Johanne MW, Lamberts, Steven WJ, Feelders, Richard A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945062/ https://www.ncbi.nlm.nih.gov/pubmed/20727199 http://dx.doi.org/10.1186/ar3118 |
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