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High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

INTRODUCTION: High mobility group box 1 (HMGB1) is released by necrotic cells or secreted in response to inflammatory stimuli. Extracellular HMGB1 may act as a pro-inflammatory cytokine in rheumatoid arthritis. We have recently reported that HMGB1 is released by osteoarthritic synoviocytes after act...

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Detalles Bibliográficos
Autores principales:	García-Arnandis, Isabel, Guillén, Maria Isabel, Gomar, Francisco, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Alcaraz, Maria José
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945068/ https://www.ncbi.nlm.nih.gov/pubmed/20799933 http://dx.doi.org/10.1186/ar3124

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