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Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study
INTRODUCTION: Streptococcus (S.) pneumoniae is the most common cause of community-acquired pneumonia. The factor V Leiden (FVL) mutation results in resistance of activated FV to inactivation by activated protein C and thereby in a prothrombotic phenotype. Human heterozygous FVL carriers have been re...
Autores principales: | Schouten, Marcel, van't Veer, Cornelis, Roelofs, Joris JTH, Levi, Marcel, van der Poll, Tom |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945128/ https://www.ncbi.nlm.nih.gov/pubmed/20682036 http://dx.doi.org/10.1186/cc9213 |
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