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Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease
BACKGROUND: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder linked to expanded CAG-triplet nucleotide repeats within the huntingtin gene. Intracellular huntingtin aggregates are present in neurons of distinct brain areas, among them regions of adult neurogenesis in...
Autores principales: | Kohl, Zacharias, Regensburger, Martin, Aigner, Robert, Kandasamy, Mahesh, Winner, Beate, Aigner, Ludwig, Winkler, Jürgen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945356/ https://www.ncbi.nlm.nih.gov/pubmed/20836877 http://dx.doi.org/10.1186/1471-2202-11-114 |
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