HMGB1 Release and Redox Regulates Autophagy and Apoptosis in Cancer Cells

The functional relationship and cross-regulation between autophagy and apoptosis is complex. Here we show that high-mobility group box 1 protein (HMGB1) is a redox-sensitive regulator of the balance between autophagy and apoptosis. In cancer cells, anti-cancer agents enhanced autophagy and apoptosis...

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Detalles Bibliográficos
Autores principales: Tang, Daolin, Kang, Rui, Cheh, Chun-Wei, Livesey, Kristen M., Liang, Xiaoyan, Schapiro, Nicole E., Benschop, Robert, Sparvero, Louis J., Amoscato, Andrew A., Tracey, Kevin J., Zeh, Herbert J., Lotze, Michael T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945431/
https://www.ncbi.nlm.nih.gov/pubmed/20622903
http://dx.doi.org/10.1038/onc.2010.261

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