Sprouty-2 Controls c-Met Expression and Metastatic Potential of Colon Cancer Cells: Sprouty/c-Met Upregulation in Human Colonic Adenocarcinomas

Sprouty negatively regulates receptor tyrosine kinase signals by inhibiting Ras/ERK pathways. Sprouty is down-regulated in breast, prostate and liver cancers and appears to function as a tumor suppressor. The role of Sprouty in colonic neoplasia, however, has not been investigated. Sprouty-2 protein...

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Detalles Bibliográficos
Autores principales: Holgren, Cory, Dougherty, Urszula, Edwin, Francis, Cerasi, Dairo, Taylor, Ieva, Fichera, Alessandro, Joseph, Loren, Bissonnette, Marc, Khare, Sharad
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945447/
https://www.ncbi.nlm.nih.gov/pubmed/20661223
http://dx.doi.org/10.1038/onc.2010.264

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