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Poliovirus replication requires the N‐terminus but not the catalytic Sec7 domain of ArfGEF GBF1

Viruses are intracellular parasites whose reproduction relies on factors provided by the host. The cellular protein GBF1 is critical for poliovirus replication. Here we show that the contribution of GBF1 to virus replication is different from its known activities in uninfected cells. Normally GBF1 a...

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Detalles Bibliográficos
Autores principales: Belov, George A., Kovtunovych, Gennadiy, Jackson, Catherine L., Ehrenfeld, Ellie
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945620/
https://www.ncbi.nlm.nih.gov/pubmed/20497182
http://dx.doi.org/10.1111/j.1462-5822.2010.01482.x

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