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Variant of Lemierre's Syndrome Secondary to Trauma

Classic Lemierre's syndrome is a septic internal jugular venous (IJV) thrombophlebitis secondary to oropharyngeal anaerobic infection in adolescent and young adult. Though upper respiratory tract infection is the most common antecedent, it has also been described following skin, soft tissues, g...

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Autores principales: Bukari, Sani M., Roxas, Renato, Kamat, Deepak
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945635/
https://www.ncbi.nlm.nih.gov/pubmed/20886053
http://dx.doi.org/10.1155/2010/123943
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author Bukari, Sani M.
Roxas, Renato
Kamat, Deepak
author_facet Bukari, Sani M.
Roxas, Renato
Kamat, Deepak
author_sort Bukari, Sani M.
collection PubMed
description Classic Lemierre's syndrome is a septic internal jugular venous (IJV) thrombophlebitis secondary to oropharyngeal anaerobic infection in adolescent and young adult. Though upper respiratory tract infection is the most common antecedent, it has also been described following skin, soft tissues, genitourinary and gastrointestinal infections. Fusobacteria necrophorum is the commonest pathogen isolated from blood and tissue cultures but other bacteria like Eikenella correndens, Bacteroides melaninogenicus and Non Group A Streptococcal species have also been reported. The overall incidence of Lemierre's and Lemierre's like syndromes has declined since the first case report in 1936. There is however, a resurgence of cases in recent years due to more judicious use of antibiotics for treatment of upper respiratory tract infection among medical practitioners. The main stay of treatment of complete Lemierre's syndrome is prolonged antibiotic coverage and surgical drainage of nonresolving abscesses. Currently, there is no consensus opinion on the use of anticoagulation in patient with complete Lemierre's syndrome complicated by septic internal jugular thrombosis and embolism. High index of suspicion is required for early diagnosis of Lemierre's and Lemierre's like syndromes. Early and effective antibiotics therapy may prevent the development full spectrum of the syndrome and its associated complication.
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spelling pubmed-29456352010-09-30 Variant of Lemierre's Syndrome Secondary to Trauma Bukari, Sani M. Roxas, Renato Kamat, Deepak Int J Pediatr Case Report Classic Lemierre's syndrome is a septic internal jugular venous (IJV) thrombophlebitis secondary to oropharyngeal anaerobic infection in adolescent and young adult. Though upper respiratory tract infection is the most common antecedent, it has also been described following skin, soft tissues, genitourinary and gastrointestinal infections. Fusobacteria necrophorum is the commonest pathogen isolated from blood and tissue cultures but other bacteria like Eikenella correndens, Bacteroides melaninogenicus and Non Group A Streptococcal species have also been reported. The overall incidence of Lemierre's and Lemierre's like syndromes has declined since the first case report in 1936. There is however, a resurgence of cases in recent years due to more judicious use of antibiotics for treatment of upper respiratory tract infection among medical practitioners. The main stay of treatment of complete Lemierre's syndrome is prolonged antibiotic coverage and surgical drainage of nonresolving abscesses. Currently, there is no consensus opinion on the use of anticoagulation in patient with complete Lemierre's syndrome complicated by septic internal jugular thrombosis and embolism. High index of suspicion is required for early diagnosis of Lemierre's and Lemierre's like syndromes. Early and effective antibiotics therapy may prevent the development full spectrum of the syndrome and its associated complication. Hindawi Publishing Corporation 2010 2010-08-31 /pmc/articles/PMC2945635/ /pubmed/20886053 http://dx.doi.org/10.1155/2010/123943 Text en Copyright © 2010 Sani M. Bukari et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bukari, Sani M.
Roxas, Renato
Kamat, Deepak
Variant of Lemierre's Syndrome Secondary to Trauma
title Variant of Lemierre's Syndrome Secondary to Trauma
title_full Variant of Lemierre's Syndrome Secondary to Trauma
title_fullStr Variant of Lemierre's Syndrome Secondary to Trauma
title_full_unstemmed Variant of Lemierre's Syndrome Secondary to Trauma
title_short Variant of Lemierre's Syndrome Secondary to Trauma
title_sort variant of lemierre's syndrome secondary to trauma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945635/
https://www.ncbi.nlm.nih.gov/pubmed/20886053
http://dx.doi.org/10.1155/2010/123943
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