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Translesion Synthesis Polymerases in the Prevention and Promotion of Carcinogenesis

A critical step in the transformation of cells to the malignant state of cancer is the induction of mutations in the DNA of cells damaged by genotoxic agents. Translesion DNA synthesis (TLS) is the process by which cells copy DNA containing unrepaired damage that blocks progression of the replicatio...

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Detalles Bibliográficos
Autores principales: Stallons, L. Jay, McGregor, W. Glenn
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945679/
https://www.ncbi.nlm.nih.gov/pubmed/20936171
http://dx.doi.org/10.4061/2010/643857

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