Cargando…

Curcumin Protects Intestinal Mucosal Barrier Function of Rat Enteritis via Activation of MKP-1 and Attenuation of p38 and NF-κB Activation

BACKGROUND: Intestinal mucosa barrier (IMB) dysfunction results in many notorious diseases for which there are currently few effective treatments. We studied curcumin's protective effect on IMB and examined its mechanism by using methotrexate (MTX) induced rat enteritis model and lipopolysaccha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Wei-Bing, Wang, Yuan-Yuan, Meng, Fan-Su, Zhang, Qing-Hua, Zeng, Jian-Ying, Xiao, Li-Ping, Yu, Xin-Pei, Peng, Dan-dan, Su, Lei, Xiao, Bing, Zhang, Zhen-Shu
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945766/ https://www.ncbi.nlm.nih.gov/pubmed/20885979 http://dx.doi.org/10.1371/journal.pone.0012969

Ejemplares similares

MKP-3 suppresses LPS-induced inflammatory responses in HUVECs via inhibition of p38 MAPK/NF-κB pathway
por: Unenkhuu, Banzragchgarav, et al.
Publicado: (2021)

MKP-1 attenuates LPS-induced blood-testis barrier dysfunction and inflammatory response through p38 and IκBα pathways
por: Pan, Yiqing, et al.
Publicado: (2016)

Luo Tong formula attenuates retinal inflammation in diabetic rats via inhibition of the p38MAPK/NF-κB pathway
por: Pang, Bing, et al.
Publicado: (2020)

Intestinal Mucosal Barrier Is Injured by BMP2/4 via Activation of NF-κB Signals after Ischemic Reperfusion
por: Chen, Kang, et al.
Publicado: (2014)

The Polyphenol Fisetin Protects Bone by Repressing NF-κB and MKP-1-Dependent Signaling Pathways in Osteoclasts
por: Léotoing, Laurent, et al.
Publicado: (2013)

Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity
por: Orr, W. Shannon, et al.
Publicado: (2013)

Regulation of Microglia Activity by Glaucocalyxin-A: Attenuation of Lipopolysaccharide-Stimulated Neuroinflammation through NF-κB and p38 MAPK Signaling Pathways
por: Kim, Byung-Wook, et al.
Publicado: (2013)

Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity
por: Haagenson, Kelly K., et al.
Publicado: (2014)

Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation
por: Francisco, Sara, et al.
Publicado: (2021)

Rubidium Chloride Targets Jnk/p38-Mediated NF-κB Activation to Attenuate Osteoclastogenesis and Facilitate Osteoblastogenesis
por: Ouyang, Zhengxiao, et al.
Publicado: (2019)

Retraction: Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity
Publicado: (2019)

Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged Mice
por: Lee, Da-Yeon, et al.
Publicado: (2023)

Erratum: Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity
por: Haagenson, Kelly K., et al.
Publicado: (2018)

Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation
por: Zhang, Bo, et al.
Publicado: (2017)

Curcumin activates autophagy and attenuates high glucose-induced apoptosis in HUVECs through the ROS/NF-κB signaling pathway
por: Jin, Qi-Hui, et al.
Publicado: (2022)

E. coli JM83 damages the mucosal barrier in Ednrb knockout mice to promote the development of Hirschsprung-associated enterocolitis via activation of TLR4/p-p38/NF-κB signaling
por: Zheng, Zebing, et al.
Publicado: (2022)

Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB
por: Linghu, Ke-Gang, et al.
Publicado: (2023)

Curcumin’s Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB Pathway
por: Zhang, Zhen-Biao, et al.
Publicado: (2018)

Paraptosis and NF-κB activation are associated with protopanaxadiol-induced cancer chemoprevention
por: Wang, Chong-Zhi, et al.
Publicado: (2013)

GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF-κB Pathways in LPS-Stimulated Microglial Cells
por: He, Gai-ying, et al.
Publicado: (2014)

Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling
por: Xu, Dan, et al.
Publicado: (2016)

Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation
por: Lee, Minho, et al.
Publicado: (2017)

Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1
por: Lehtola, Tiina, et al.
Publicado: (2022)

Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimer's disease
por: Shen, Qi, et al.
Publicado: (2020)

Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE(−/−) mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation
por: Feng, Dan, et al.
Publicado: (2019)

Impact of ozone exposure on the response to glucocorticoid in a mouse model of asthma: involvements of p38 MAPK and MKP-1
por: Bao, Aihua, et al.
Publicado: (2014)

Exclusive enteral nutrition protects against inflammatory bowel disease by inhibiting NF-κB activation through regulation of the p38/MSK1 pathway
por: Yu, Ting, et al.
Publicado: (2018)

Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease
por: Deuring, J. Jasper, et al.
Publicado: (2019)

Higenamine Attenuates Neuropathic Pain by Inhibition of NOX2/ROS/TRP/P38 Mitogen-Activated Protein Kinase/NF-ĸB Signaling Pathway
por: Yang, Bing, et al.
Publicado: (2021)

Effects of curcumin on the apoptosis of cardiomyocytes and the expression of NF-κB, PPAR-γ and Bcl-2 in rats with myocardial infarction injury
por: Lv, Feng-Hua, et al.
Publicado: (2016)

Cloning, expression pattern, and potential role of MAPKp38 and NF-κBp65 in response to lipopolysaccharide in yellow catfish (Pelteobagrus fulvidraco)
por: Shi, Dan, et al.
Publicado: (2019)

Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation
por: Gan, Zhongyuan, et al.
Publicado: (2018)

Gold Clusters Attenuate Inflammation in Rat Mesangial Cells via Inhibiting the Activation of NF-κB Pathway
por: Yuan, Jinling, et al.
Publicado: (2020)

Curcumin improves expression of SCF/c-kit through attenuating oxidative stress and NF-κB activation in gastric tissues of diabetic gastroparesis rats
por: Jin, Qi-Hui, et al.
Publicado: (2013)

5-Fluorouracil Induces Enteric Neuron Death and Glial Activation During Intestinal Mucositis via a S100B-RAGE-NFκB-Dependent Pathway
por: Costa, Deiziane V. S., et al.
Publicado: (2019)

Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-κB and p38 MAPK pathways in LPS-activated RAW264.7 macrophages
por: Pang, Min, et al.
Publicado: (2017)

MKP-4 suppresses hepatocarcinogenesis by targeting ERK1/2 pathway
por: Shen, Zhongyi, et al.
Publicado: (2019)

Resistin Promotes Nasopharyngeal Carcinoma Metastasis through TLR4-Mediated Activation of p38 MAPK/NF-κB Signaling Pathway
por: Zhang, Zongmeng, et al.
Publicado: (2022)

Anisomycin protects against sepsis by attenuating IκB kinase-dependent NF-κB activation and inflammatory gene expression
por: Park, Gyoung Lim, et al.
Publicado: (2021)

p38/MKP-1–regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair
por: Perdiguero, Eusebio, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ul57v0durvg3mtfuvn5dtea6jg