Cloud-scale RNA-sequencing differential expression analysis with Myrna

As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the a...

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Detalles Bibliográficos
Autores principales: Langmead, Ben, Hansen, Kasper D, Leek, Jeffrey T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945785/
https://www.ncbi.nlm.nih.gov/pubmed/20701754
http://dx.doi.org/10.1186/gb-2010-11-8-r83
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author Langmead, Ben
Hansen, Kasper D
Leek, Jeffrey T
author_facet Langmead, Ben
Hansen, Kasper D
Leek, Jeffrey T
author_sort Langmead, Ben
collection PubMed
description As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from http://bowtie-bio.sf.net/myrna.
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spelling pubmed-29457852010-10-07 Cloud-scale RNA-sequencing differential expression analysis with Myrna Langmead, Ben Hansen, Kasper D Leek, Jeffrey T Genome Biol Software As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from http://bowtie-bio.sf.net/myrna. BioMed Central 2010 2010-08-11 /pmc/articles/PMC2945785/ /pubmed/20701754 http://dx.doi.org/10.1186/gb-2010-11-8-r83 Text en Copyright ©2010 Langmead et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Langmead, Ben
Hansen, Kasper D
Leek, Jeffrey T
Cloud-scale RNA-sequencing differential expression analysis with Myrna
title Cloud-scale RNA-sequencing differential expression analysis with Myrna
title_full Cloud-scale RNA-sequencing differential expression analysis with Myrna
title_fullStr Cloud-scale RNA-sequencing differential expression analysis with Myrna
title_full_unstemmed Cloud-scale RNA-sequencing differential expression analysis with Myrna
title_short Cloud-scale RNA-sequencing differential expression analysis with Myrna
title_sort cloud-scale rna-sequencing differential expression analysis with myrna
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945785/
https://www.ncbi.nlm.nih.gov/pubmed/20701754
http://dx.doi.org/10.1186/gb-2010-11-8-r83
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