Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract

SMAD4 acts as the converging point for TGFβ and BMP signaling in heart development. Here, we investigated the role of SMAD4 in heart development using a novel α skeletal muscle actin Cre recombinase (MuCre) transgenic mouse strain. Lineage tracing using MuCre/ROSA26(LacZ) reporter mice indicated str...

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Detalles Bibliográficos
Autores principales: Azhar, Mohamad, Wang, Pei-Yu, Frugier, Tony, Koishi, Kyoko, Deng, Chuxia, Noakes, Peter G., McLennan, Ian S.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2010
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945925/
https://www.ncbi.nlm.nih.gov/pubmed/20877696

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