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Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport

Gram-negative bacteria, such as Escherichia coli, frequently utilize tripartite efflux complexes in the resistance-nodulation-cell division (RND) family to expel diverse toxic compounds from the cell.1,2 The efflux system CusCBA is responsible for extruding biocidal Cu(I) and Ag(I) ions.3,4 No prior...

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Detalles Bibliográficos
Autores principales: Long, Feng, Su, Chih-Chia, Zimmermann, Michael T., Boyken, Scott E., Rajashankar, Kanagalaghatta R., Jernigan, Robert L., Yu, Edward W.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946090/
https://www.ncbi.nlm.nih.gov/pubmed/20865003
http://dx.doi.org/10.1038/nature09395