Targeting pathophysiological rhythms: prednisone chronotherapy shows sustained efficacy in rheumatoid arthritis

OBJECTIVE: This 9-month open-label extension of the Circadian Administration of Prednisone in Rheumatoid Arthritis Study (CAPRA 1) investigated the long-term safety and efficacy of prednisone chronotherapy with a novel modified-release (MR) prednisone for up to 12 months. METHODS: Of 288 patients wi...

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Detalles Bibliográficos
Autores principales: Buttgereit, Frank, Doering, Gisela, Schaeffler, Achim, Witte, Stephan, Sierakowski, Stanislaw, Gromnica-Ihle, Erika, Jeka, Slawomir, Krueger, Klaus, Szechinski, Jacek, Alten, Rieke
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946119/
https://www.ncbi.nlm.nih.gov/pubmed/20542963
http://dx.doi.org/10.1136/ard.2009.126888

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