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Silencing Dkk1 expression rescues dexamethasone-induced suppression of primary human osteoblast differentiation
BACKGROUND: The Wnt/β-catenin pathway is a major signaling cascade in bone biology, playing a key role in bone development and remodeling. The objectives of this study were firstly, to determine the effects of dexamethasone exposure on Wnt/β-catenin signaling at an intracellular and transcriptional...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946271/ https://www.ncbi.nlm.nih.gov/pubmed/20843343 http://dx.doi.org/10.1186/1471-2474-11-210 |