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Silencing Dkk1 expression rescues dexamethasone-induced suppression of primary human osteoblast differentiation

BACKGROUND: The Wnt/β-catenin pathway is a major signaling cascade in bone biology, playing a key role in bone development and remodeling. The objectives of this study were firstly, to determine the effects of dexamethasone exposure on Wnt/β-catenin signaling at an intracellular and transcriptional...

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Detalles Bibliográficos
Autores principales:	Butler, Joseph S, Queally, Joseph M, Devitt, Brian M, Murray, David W, Doran, Peter P, O'Byrne, John M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946271/ https://www.ncbi.nlm.nih.gov/pubmed/20843343 http://dx.doi.org/10.1186/1471-2474-11-210

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