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Augmentation of neovascularization in murine hindlimb ischemia by combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells transplantation
OBJECTIVES: We postulated that combining high-dose simvastatin with bone marrow derived-mesenchymal stem cells (MSCs) delivery may give better prognosis in a mouse hindlimb ischemia model. METHODS: Mouse hindlimb ischemia model was established by ligating the right femoral artery. Animals were group...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946286/ https://www.ncbi.nlm.nih.gov/pubmed/20846454 http://dx.doi.org/10.1186/1423-0127-17-75 |