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Augmentation of neovascularization in murine hindlimb ischemia by combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells transplantation

OBJECTIVES: We postulated that combining high-dose simvastatin with bone marrow derived-mesenchymal stem cells (MSCs) delivery may give better prognosis in a mouse hindlimb ischemia model. METHODS: Mouse hindlimb ischemia model was established by ligating the right femoral artery. Animals were group...

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Detalles Bibliográficos
Autores principales:	Li, Yong, Zhang, Dingguo, Zhang, Yuqing, He, Guoping, Zhang, Fumin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946286/ https://www.ncbi.nlm.nih.gov/pubmed/20846454 http://dx.doi.org/10.1186/1423-0127-17-75

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