IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level

Accumulation of unfolded proteins in the endoplasmic reticulum (ER) causes ER stress. As a cellular adaptive response to ER stress, unfolded protein response (UPR) activates molecules for the quality control of ER proteins. One enzyme that plays an important role in UPR is Inositol Requiring Enzyme-...

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Detalles Bibliográficos
Autores principales: Iwawaki, Takao, Akai, Ryoko, Kohno, Kenji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946364/
https://www.ncbi.nlm.nih.gov/pubmed/20885949
http://dx.doi.org/10.1371/journal.pone.0013052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946364/
https://www.ncbi.nlm.nih.gov/pubmed/20885949
http://dx.doi.org/10.1371/journal.pone.0013052

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