A Common Variant in the Telomerase RNA Component Is Associated with Short Telomere Length

BACKGROUND: Telomeres shorten as cells divide. This shortening is compensated by the enzyme telomerase. We evaluated the effect of common variants in the telomerase RNA component (TERC) gene on telomere length (TL) in the population-based Health Aging and Body Composition (Health ABC) Study and in t...

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Detalles Bibliográficos
Autores principales: Njajou, Omer T., Blackburn, Elizabeth H., Pawlikowska, Ludmila, Mangino, Massimo, Damcott, Coleen M., Kwok, Pui-Yan, Spector, Timothy D., Newman, Anne B., Harris, Tamara B., Cummings, Steven R., Cawthon, Richard M., Shuldiner, Alan R., Valdes, Ana M., Hsueh, Wen-Chi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946401/
https://www.ncbi.nlm.nih.gov/pubmed/20885959
http://dx.doi.org/10.1371/journal.pone.0013048

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