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Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP(+) Toxicity in Neuronal Cells

Mitochondrial dysfunction is involved in the pathogenesis of neurodegenerative diseases, including Parkinson’s disease (PD). Uncoupling proteins (UCPs) delink ATP production from biofuel oxidation in mitochondria to reduce oxidative stress. UCP2 is expressed in brain, and has neuroprotective effects...

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Detalles Bibliográficos
Autores principales:	Ho, Philip Wing-Lok, Liu, Hui-Fang, Ho, Jessica Wing-Man, Zhang, Wei-Yi, Chu, Andrew Chi-Yuen, Kwok, Ken Hon-Hung, Ge, Xuan, Chan, Koon-Ho, Ramsden, David Boyer, Ho, Shu-Leong
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946553/ https://www.ncbi.nlm.nih.gov/pubmed/19763737 http://dx.doi.org/10.1007/s12640-009-9109-y

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