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Synthesis and Optimization of the Labeling Procedure of (99m)Tc-Hynic-Interleukin-2 for In vivo Imaging of Activated T lymphocytes

INTRODUCTION: We have previously described the labeling of interleukin-2 (IL2) with (123)I and (99m)Tc-N(3)S. Both radiopharmaceuticals were successfully applied in humans to image several inflammatory lesions and autoimmune diseases characterized by tissue infiltrating lymphocytes expressing the IL...

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Detalles Bibliográficos
Autores principales:	D’Alessandria, Calogero, di Gialleonardo, Valentina, Chianelli, Marco, Mather, Stephen J., de Vries, Erik F. J., Scopinaro, Francesco, Dierck, Rudi A., Signore, Alberto
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946565/ https://www.ncbi.nlm.nih.gov/pubmed/19949980 http://dx.doi.org/10.1007/s11307-009-0285-1

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