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PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex

The peroxisome proliferator-activated receptor-α (PPARα) plays a key role in lipid metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the development of hepatocellular carcinomas. The ability of PPARα to induce expression of its target genes depends on Mediator, an evo...

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Detalles Bibliográficos
Autores principales: Pyper, Sean R., Viswakarma, Navin, Jia, Yuzhi, Zhu, Yi-Jun, Fondell, Joseph D., Reddy, Janardan K.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946606/
https://www.ncbi.nlm.nih.gov/pubmed/20885938
http://dx.doi.org/10.1155/2010/173907