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PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex
The peroxisome proliferator-activated receptor-α (PPARα) plays a key role in lipid metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the development of hepatocellular carcinomas. The ability of PPARα to induce expression of its target genes depends on Mediator, an evo...
Autores principales: | Pyper, Sean R., Viswakarma, Navin, Jia, Yuzhi, Zhu, Yi-Jun, Fondell, Joseph D., Reddy, Janardan K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946606/ https://www.ncbi.nlm.nih.gov/pubmed/20885938 http://dx.doi.org/10.1155/2010/173907 |
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