Efficient Transduction of Feline Neural Progenitor Cells for Delivery of Glial Cell Line-Derived Neurotrophic Factor Using a Feline Immunodeficiency Virus-Based Lentiviral Construct

Work has shown that stem cell transplantation can rescue or replace neurons in models of retinal degenerative disease. Neural progenitor cells (NPCs) modified to overexpress neurotrophic factors are one means of providing sustained delivery of therapeutic gene products in vivo. To develop a nonroden...

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Detalles Bibliográficos
Autores principales: You, X. Joann, Gu, Ping, Wang, Jinmei, Song, Tianran, Yang, Jing, Liew, Chee Gee, Klassen, Henry
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946610/
https://www.ncbi.nlm.nih.gov/pubmed/20936061
http://dx.doi.org/10.1155/2011/378965

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