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Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction
We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STE...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946655/ https://www.ncbi.nlm.nih.gov/pubmed/20890426 http://dx.doi.org/10.3346/jkms.2010.25.10.1456 |
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author | Lee, Min Goo Jeong, Myung Ho Ahn, Youngkeun Chae, Shung Chull Hur, Seung Ho Hong, Taek Jong Kim, Young Jo Seong, In Whan Chae, Jei Keon Rhew, Jay Young Chae, In Ho Cho, Myeong Chan Bae, Jang Ho Rha, Seung Woon Kim, Chong Jin Choi, Donghoon Jang, Yang Soo Yoon, Junghan Chung, Wook Sung Cho, Jeong Gwan Seung, Ki Bae Park, Seung Jung |
author_facet | Lee, Min Goo Jeong, Myung Ho Ahn, Youngkeun Chae, Shung Chull Hur, Seung Ho Hong, Taek Jong Kim, Young Jo Seong, In Whan Chae, Jei Keon Rhew, Jay Young Chae, In Ho Cho, Myeong Chan Bae, Jang Ho Rha, Seung Woon Kim, Chong Jin Choi, Donghoon Jang, Yang Soo Yoon, Junghan Chung, Wook Sung Cho, Jeong Gwan Seung, Ki Bae Park, Seung Jung |
author_sort | Lee, Min Goo |
collection | PubMed |
description | We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STEMI) between November 2005 and December 2006 were categorized according to the National Cholesterol Education Program-Adult Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac events (MACE) during one-year follow-up. Patients were grouped based on existence of MS: group I: MS (n=1,182, 777 men, 62.8±12.3 yr); group II: Non-MS (n=808, 675 men, 64.2±13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (P=0.005). There were no differences between two groups in the coronary angiographic findings except for multivessel involvement (P=0.01). The incidence of in-hospital death was higher in group I than in group II (P=0.047), but the rates of composite MACE during one-year clinical follow-up showed no significant differences. Multivariate analysis showed that low LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement were associated with high in-hospital death rate. In conclusion, MS is an important predictor for in-hospital death in patients with STEMI. |
format | Text |
id | pubmed-2946655 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-29466552010-10-02 Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction Lee, Min Goo Jeong, Myung Ho Ahn, Youngkeun Chae, Shung Chull Hur, Seung Ho Hong, Taek Jong Kim, Young Jo Seong, In Whan Chae, Jei Keon Rhew, Jay Young Chae, In Ho Cho, Myeong Chan Bae, Jang Ho Rha, Seung Woon Kim, Chong Jin Choi, Donghoon Jang, Yang Soo Yoon, Junghan Chung, Wook Sung Cho, Jeong Gwan Seung, Ki Bae Park, Seung Jung J Korean Med Sci Original Article We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STEMI) between November 2005 and December 2006 were categorized according to the National Cholesterol Education Program-Adult Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac events (MACE) during one-year follow-up. Patients were grouped based on existence of MS: group I: MS (n=1,182, 777 men, 62.8±12.3 yr); group II: Non-MS (n=808, 675 men, 64.2±13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (P=0.005). There were no differences between two groups in the coronary angiographic findings except for multivessel involvement (P=0.01). The incidence of in-hospital death was higher in group I than in group II (P=0.047), but the rates of composite MACE during one-year clinical follow-up showed no significant differences. Multivariate analysis showed that low LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement were associated with high in-hospital death rate. In conclusion, MS is an important predictor for in-hospital death in patients with STEMI. The Korean Academy of Medical Sciences 2010-10 2010-09-17 /pmc/articles/PMC2946655/ /pubmed/20890426 http://dx.doi.org/10.3346/jkms.2010.25.10.1456 Text en © 2010 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lee, Min Goo Jeong, Myung Ho Ahn, Youngkeun Chae, Shung Chull Hur, Seung Ho Hong, Taek Jong Kim, Young Jo Seong, In Whan Chae, Jei Keon Rhew, Jay Young Chae, In Ho Cho, Myeong Chan Bae, Jang Ho Rha, Seung Woon Kim, Chong Jin Choi, Donghoon Jang, Yang Soo Yoon, Junghan Chung, Wook Sung Cho, Jeong Gwan Seung, Ki Bae Park, Seung Jung Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction |
title | Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction |
title_full | Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction |
title_fullStr | Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction |
title_full_unstemmed | Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction |
title_short | Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction |
title_sort | impact of the metabolic syndrome on the clinical outcome of patients with acute st-elevation myocardial infarction |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946655/ https://www.ncbi.nlm.nih.gov/pubmed/20890426 http://dx.doi.org/10.3346/jkms.2010.25.10.1456 |
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