Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection

Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection compli...

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Autores principales: Cho, Eunjung, Cha, Inhye, Yoon, Kichul, Yang, Ha Na, Kim, Hye Won, Kim, Myung-Gyu, Jo, Sang-Kyung, Cho, Won Yong, Kim, Hyoung Kyu
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946668/
https://www.ncbi.nlm.nih.gov/pubmed/20890439
http://dx.doi.org/10.3346/jkms.2010.25.10.1529
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author Cho, Eunjung
Cha, Inhye
Yoon, Kichul
Yang, Ha Na
Kim, Hye Won
Kim, Myung-Gyu
Jo, Sang-Kyung
Cho, Won Yong
Kim, Hyoung Kyu
author_facet Cho, Eunjung
Cha, Inhye
Yoon, Kichul
Yang, Ha Na
Kim, Hye Won
Kim, Myung-Gyu
Jo, Sang-Kyung
Cho, Won Yong
Kim, Hyoung Kyu
author_sort Cho, Eunjung
collection PubMed
description Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection complicated by dialysis-dependent AKI. His kidney biopsy showed acute tubulointerstitial nephritis with massive infiltration of activated macrophages and T cells, and he progressively demonstrated features of VAHS. With hemodialysis and steroid treatment, he was successfully recovered.
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spelling pubmed-29466682010-10-02 Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection Cho, Eunjung Cha, Inhye Yoon, Kichul Yang, Ha Na Kim, Hye Won Kim, Myung-Gyu Jo, Sang-Kyung Cho, Won Yong Kim, Hyoung Kyu J Korean Med Sci Case Report Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by virus-associated hemophagocytic syndrome (VAHS). Our patient, a 48-yr-old man, was diagnosed with HAV infection complicated by dialysis-dependent AKI. His kidney biopsy showed acute tubulointerstitial nephritis with massive infiltration of activated macrophages and T cells, and he progressively demonstrated features of VAHS. With hemodialysis and steroid treatment, he was successfully recovered. The Korean Academy of Medical Sciences 2010-10 2010-09-17 /pmc/articles/PMC2946668/ /pubmed/20890439 http://dx.doi.org/10.3346/jkms.2010.25.10.1529 Text en © 2010 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cho, Eunjung
Cha, Inhye
Yoon, Kichul
Yang, Ha Na
Kim, Hye Won
Kim, Myung-Gyu
Jo, Sang-Kyung
Cho, Won Yong
Kim, Hyoung Kyu
Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
title Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
title_full Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
title_fullStr Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
title_full_unstemmed Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
title_short Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
title_sort hemophagocytic syndrome in a patient with acute tubulointerstitial nephritis secondary to hepatitis a virus infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946668/
https://www.ncbi.nlm.nih.gov/pubmed/20890439
http://dx.doi.org/10.3346/jkms.2010.25.10.1529
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