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Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania

AIMS: The aim of this study was to determine the incidence of humans being bitten by rabies-suspected animals, and the victims’ adherence to post-exposure prophylaxis (PEP) regimen. MATERIALS AND METHODS: A retrospective analysis of data of victims treated at Bugando Medical Centre during the period...

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Autores principales: Mazigo, Humphrey D, Okumu, Fredros O, Kweka, Eliningaya J, Mnyone, Ladslaus L
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946675/
https://www.ncbi.nlm.nih.gov/pubmed/20927280
http://dx.doi.org/10.4103/0974-777X.68530
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author Mazigo, Humphrey D
Okumu, Fredros O
Kweka, Eliningaya J
Mnyone, Ladslaus L
author_facet Mazigo, Humphrey D
Okumu, Fredros O
Kweka, Eliningaya J
Mnyone, Ladslaus L
author_sort Mazigo, Humphrey D
collection PubMed
description AIMS: The aim of this study was to determine the incidence of humans being bitten by rabies-suspected animals, and the victims’ adherence to post-exposure prophylaxis (PEP) regimen. MATERIALS AND METHODS: A retrospective analysis of data of victims treated at Bugando Medical Centre during the period 2002-2006 (n=5 years) was done. RESULTS: A total of 767 bite injuries inflicted by rabies-suspected animals were reported, giving a mean annual incidence of ~58 cases per 100,000 (52.5% males, 47.5% females). The proportion of children bitten was relatively higher than that of adults. All victims were treated by using inactivated diploid-cell rabies vaccine and were recommended to appear for the second and third doses. However, only 28% of the victims completed the vaccination regime. Domestic dogs were involved in 95.44% of the human bite cases, whereas cats (3.9%), spotted hyena (Crocuta crocuta) (0.03%), vervet monkey (Cercopithecur aethiops) (0.01%) and black-backed jackal (0.01%) played a minor role. The majority of rabies-suspected case reports were from Nyamagana district and occurred most frequently from June to October each year. CONCLUSIONS: In conclusion, this study revealed that incidences of humans being bitten by dogs suspected of rabies are common in Tanzania, involve mostly children, and victims do not comply with the prophylactic regimen. Rigorous surveillance to determine the status of rabies and the risk factors for human rabies, as well as formulation and institution of appropriate rabies-control policies, is required.
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spelling pubmed-29466752010-10-06 Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania Mazigo, Humphrey D Okumu, Fredros O Kweka, Eliningaya J Mnyone, Ladslaus L J Glob Infect Dis Original Article AIMS: The aim of this study was to determine the incidence of humans being bitten by rabies-suspected animals, and the victims’ adherence to post-exposure prophylaxis (PEP) regimen. MATERIALS AND METHODS: A retrospective analysis of data of victims treated at Bugando Medical Centre during the period 2002-2006 (n=5 years) was done. RESULTS: A total of 767 bite injuries inflicted by rabies-suspected animals were reported, giving a mean annual incidence of ~58 cases per 100,000 (52.5% males, 47.5% females). The proportion of children bitten was relatively higher than that of adults. All victims were treated by using inactivated diploid-cell rabies vaccine and were recommended to appear for the second and third doses. However, only 28% of the victims completed the vaccination regime. Domestic dogs were involved in 95.44% of the human bite cases, whereas cats (3.9%), spotted hyena (Crocuta crocuta) (0.03%), vervet monkey (Cercopithecur aethiops) (0.01%) and black-backed jackal (0.01%) played a minor role. The majority of rabies-suspected case reports were from Nyamagana district and occurred most frequently from June to October each year. CONCLUSIONS: In conclusion, this study revealed that incidences of humans being bitten by dogs suspected of rabies are common in Tanzania, involve mostly children, and victims do not comply with the prophylactic regimen. Rigorous surveillance to determine the status of rabies and the risk factors for human rabies, as well as formulation and institution of appropriate rabies-control policies, is required. Medknow Publications 2010 /pmc/articles/PMC2946675/ /pubmed/20927280 http://dx.doi.org/10.4103/0974-777X.68530 Text en © Journal of Global Infectious Diseases http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mazigo, Humphrey D
Okumu, Fredros O
Kweka, Eliningaya J
Mnyone, Ladslaus L
Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania
title Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania
title_full Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania
title_fullStr Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania
title_full_unstemmed Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania
title_short Retrospective Analysis of Suspected Rabies Cases Reported at Bugando Referral Hospital, Mwanza, Tanzania
title_sort retrospective analysis of suspected rabies cases reported at bugando referral hospital, mwanza, tanzania
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946675/
https://www.ncbi.nlm.nih.gov/pubmed/20927280
http://dx.doi.org/10.4103/0974-777X.68530
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