Unraveling the Genetic Basis of Asthma and Allergic Diseases

Asthma and allergic diseases are believed to be complex genetic diseases which may result from the interaction of multiple genetic factors and environmental stimuli. In past decades, great efforts have been exerted in unraveling their genetic basis. The strategies in discovering genes and genetic va...

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Detalles Bibliográficos
Autores principales: Meng, Jian-Feng, Rosenwasser, Lanny J
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946699/
https://www.ncbi.nlm.nih.gov/pubmed/20885906
http://dx.doi.org/10.4168/aair.2010.2.4.215
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author Meng, Jian-Feng
Rosenwasser, Lanny J
author_facet Meng, Jian-Feng
Rosenwasser, Lanny J
author_sort Meng, Jian-Feng
collection PubMed
description Asthma and allergic diseases are believed to be complex genetic diseases which may result from the interaction of multiple genetic factors and environmental stimuli. In past decades, great efforts have been exerted in unraveling their genetic basis. The strategies in discovering genes and genetic variants, confirming their importance in pathogenesis of asthma and allergic diseases, as well as their strengths and limitations are summarized comprehensively and concisely. The current consensus about the genetic basis of asthma and allergic diseases is briefly described as well.
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spelling pubmed-29466992010-10-01 Unraveling the Genetic Basis of Asthma and Allergic Diseases Meng, Jian-Feng Rosenwasser, Lanny J Allergy Asthma Immunol Res Review Asthma and allergic diseases are believed to be complex genetic diseases which may result from the interaction of multiple genetic factors and environmental stimuli. In past decades, great efforts have been exerted in unraveling their genetic basis. The strategies in discovering genes and genetic variants, confirming their importance in pathogenesis of asthma and allergic diseases, as well as their strengths and limitations are summarized comprehensively and concisely. The current consensus about the genetic basis of asthma and allergic diseases is briefly described as well. The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2010-10 2010-06-11 /pmc/articles/PMC2946699/ /pubmed/20885906 http://dx.doi.org/10.4168/aair.2010.2.4.215 Text en Copyright © 2010 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Meng, Jian-Feng
Rosenwasser, Lanny J
Unraveling the Genetic Basis of Asthma and Allergic Diseases
title Unraveling the Genetic Basis of Asthma and Allergic Diseases
title_full Unraveling the Genetic Basis of Asthma and Allergic Diseases
title_fullStr Unraveling the Genetic Basis of Asthma and Allergic Diseases
title_full_unstemmed Unraveling the Genetic Basis of Asthma and Allergic Diseases
title_short Unraveling the Genetic Basis of Asthma and Allergic Diseases
title_sort unraveling the genetic basis of asthma and allergic diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946699/
https://www.ncbi.nlm.nih.gov/pubmed/20885906
http://dx.doi.org/10.4168/aair.2010.2.4.215
work_keys_str_mv AT mengjianfeng unravelingthegeneticbasisofasthmaandallergicdiseases
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