Leishmania-Specific Surface Antigens Show Sub-Genus Sequence Variation and Immune Recognition

BACKGROUND: A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania species. While HASPs are antigenic in t...

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Detalles Bibliográficos
Autores principales: Depledge, Daniel P., MacLean, Lorna M., Hodgkinson, Michael R., Smith, Barbara A., Jackson, Andrew P., Ma, Saufung, Uliana, Silvia R. B., Smith, Deborah F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946902/
https://www.ncbi.nlm.nih.gov/pubmed/20927190
http://dx.doi.org/10.1371/journal.pntd.0000829

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