Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa

Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. I...

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Detalles Bibliográficos
Autores principales: de Jong, Bouke C., Antonio, Martin, Gagneux, Sebastien
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946903/
https://www.ncbi.nlm.nih.gov/pubmed/20927191
http://dx.doi.org/10.1371/journal.pntd.0000744
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author de Jong, Bouke C.
Antonio, Martin
Gagneux, Sebastien
author_facet de Jong, Bouke C.
Antonio, Martin
Gagneux, Sebastien
author_sort de Jong, Bouke C.
collection PubMed
description Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto.
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spelling pubmed-29469032010-10-06 Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa de Jong, Bouke C. Antonio, Martin Gagneux, Sebastien PLoS Negl Trop Dis Review Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto. Public Library of Science 2010-09-28 /pmc/articles/PMC2946903/ /pubmed/20927191 http://dx.doi.org/10.1371/journal.pntd.0000744 Text en de Jong et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Review
de Jong, Bouke C.
Antonio, Martin
Gagneux, Sebastien
Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa
title Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa
title_full Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa
title_fullStr Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa
title_full_unstemmed Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa
title_short Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa
title_sort mycobacterium africanum—review of an important cause of human tuberculosis in west africa
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946903/
https://www.ncbi.nlm.nih.gov/pubmed/20927191
http://dx.doi.org/10.1371/journal.pntd.0000744
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